https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Airway gene expression identifies subtypes of type 2 inflammation in severe asthma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45666 Wed 02 Nov 2022 15:59:10 AEDT ]]> Relationship of sputum mast cells with clinical and inflammatory characteristics of asthma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46094 1 and FVC. Trends towards similar clinical associations with elevated MCs were observed in a paucigranulocytic subpopulation (n = 15) lacking airway eosinophilia or neutrophilia. Receiver operator characteristic (ROC) analysis showed peripheral blood eosinophil (PBE) count predicted elevated sputum eosinophils and basophils, but not MCs. Conclusions and Clinical Relevance: Sputum MCs are elevated in asthma, and their measurement may be useful as they relate to key clinical features of asthma (spirometry, asthma control, AHR). PBE count did not predict airway MC status, suggesting direct measurement of airway MCs by sensitive methods such as flow cytometry should be further developed.]]> Tue 21 May 2024 11:55:14 AEST ]]> The role of STATs in the interaction of virus and type 2 cytokines in airway epithelial cells https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:55557 Thu 06 Jun 2024 13:16:14 AEST ]]>